1Center for Traditional Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
2College of Chinese Medicine, China Medical University, Taipei, Taiwan
3Insitiute of Traditional Medicine, National Yang-Ming Univerdity, Taipei, Taiwan
4School of Medicine, National Yang-Ming Univerdity, Taipei, Taiwan
【Summary】
Vogt-Koyanagi-Harada Disease (VKHD) is a multisystem autoimmune disease that occurs mainly in people of color. It’s characterized by uveitis with serous retinal detachment, and is often accompanied by neurology (neck stiffness, cerebrospinal fluid increase, meningitis) and skin(vitiligo, alopecia) related symptoms. Depending on the stage of disease, the clinical manifestations perform diverse, and the clinical symptom of Chinese medicine also change: the acute phase perform damp-heat in liver channel, and the recovery period perform deficiency of liver-yin and kidney-yin.
This case report showed a 57-year-old male came to the hospital’s traditional medicine department in April 2011 due to blurred vision of both eyes. On June 30,2010, this patient suffered from Vogt-Koyanagi-Harada disease, the clinical manifestations perform tearing eyes, blurred vision, photophobia, etc. The fundus of eyes showed serous retinal detachment, and optical coherence tomography (OCT) showed subretinal fluid OU, and fluorescein angiography showed fluorescent point. Prednisolone and Sandimmun neural was given in the period of acute phase, and symptomatic treatment done in recovery period. Chinese medicine treatment for a period of 9 months (2011/4/18-2012/1/19), the principles of treatment was supplementing qi and nourishing yin, dispersing liver qi and heat-clearing. We used xiao chai hu tang combined with zhu ye shi gao tang. The results showed that the patient’s corrected visual could maintain OD 1.2 amd OS 0.9, indicating that Chinese herbal medicine combined with western medicine ophthalmology treatment could improve the quality of life of patients with Harada’s disease.
Keywords:Vogt-Koyanagi-Harada Disease, uveitis, scientifically processed Chinese herbal medication, xiao chai hu tang combined with zhu ye shi gao tang