中醫藥研究論叢

202.14 保和丸於胰臟惡性腫瘤末期運用之病例探討

 

保和丸於胰臟惡性腫瘤末期運用之病例探討
Treatment of Advanced Pancreatic Carcinoma Patients with Baohe Pills: A Case Report
廖翊芳1 陳金女2 賴榮年1,3,4*
1 中國醫藥大學中醫學系,台中,台灣
2 中國醫藥大學中西醫結合研究所,台中,台灣
3 中國醫藥大學附設醫院中西醫結合科,台中,台灣
4 台灣中醫家庭醫學醫學會,台北,台灣
【摘要】
胰臟惡性腫瘤的61 歲女性,分析其癌症末期死亡前318 天的就診用藥,接受中西醫合併治療共58 日,在病患腎絲球過濾率下降到69 的時候,服用39 天的保和丸共248 公克,腎絲球過濾率上升到96。顯示中西藥併用不但沒有腎臟毒性的交互作用,而且保和丸在胰臟癌末期可能具有保護腎絲球免於損害的保護作用,結論:胰臟惡性腫瘤末期的病患如果腸胃功能不好、食慾不振,保和丸為一安全可以搭配併服用的中藥方劑。
【關鍵詞】
保和丸、胰臟惡性腫瘤、腎絲球過濾率
 
Yi-Fang Liao1 Chin-Nu Chen2 Jung-Nien Lai1,3,4*
1School of Chinese Medicine, China Medical University, Taichung, Taiwan
2Graduate Institute of Integrated Medicine, China Medical University, Taichung, Taiwan
3Department of Integrated Chinese and Western Medicine, China Medical University
Hospital, Taichung, Taiwan
4Taiwan Association for Traditional Chinese Medicine of Family, Taipei, Taiwan
【Summary】
We would like to report for what TCM practitioners may experience as a 61-year-old female patient goes through the end stages of pancreatic cancer. The retrospective chart was reviewed and we found that she received 58-day traditional Chinese herbal products in 318-day medical record before her death. Interestingly, her estimated glomerular filtration rate (eGFR) was from 69 mL/ min/1.73 m2 to 96 mL/min/1.73 m2 after taking 248-gram of Baohe pills (totally 39 days). This result infers that Baohe pills might be a safe choice in treating gastrointestinal upset for pancreatic patient who were receiving nephrotoxic chemotherapeutic regimen.
Keywords:Baohe pills, Pancreatic cancer, Glomerular Filtration Rate