中醫藥研究論叢

212.2 中醫藥輔助治療化療不適後生活品質改善與用藥模式比較探討-乳癌住院患者 前瞻式單臂世代研究

 

TJ TCM.21(2) : 09-22, 2018
中醫藥輔助治療化療不適後生活品質改善與用藥模式比較探討
-乳癌住院患者前瞻式單臂世代研究
A Comparative Study on the Improvementof Quality of Life and Medication PatternAfter Adjuvant Chemotherapy for ChineseMedicine: A Prospective Cohort Study ofBreast Cancer Patients
陳韋任1,2 廖啟卉3 鄭秝丞1,4 李欣樺1 陳柏全1*
1 佛教慈濟醫療財團法人大林慈濟醫院中醫部,嘉義,台灣
2 國立成功大學工業衛生學科暨環境醫學研究所,台南,台灣
3 奇美醫療財團法人奇美醫院中醫部,台南,台灣
4 國立成功大學老年學研究所,台南,台灣
【摘要】
前言:乳癌已是全球女性最常見的癌症,我國約每47 分鐘就有一位女性罹患乳癌,平均發生年齡約為54 歲,其中以45~65 歲之間為發生高峰,雖然相較於國外,我國女性的乳癌發生率不若西方女性高,或許因為飲食西化、晚婚晚孕等影響,乳癌罹癌率近年不只年輕化,且有逐年上升的趨勢。最近的癌症登記統計以及國人十大死因報告,乳癌發生率、死亡率十年成長幅度皆為癌症之首。乳癌現行常規治療以化學治療、放射線療法及手術廓清為主,然而不論是在乳癌的症狀,抑或是手術、化、放療的副作用,對患者所帶來的不適症狀,皆影響其生活品質,甚至使患者對治療怯步,也大大的影響患者的治療意願及預後。
方法:本研究採用類實驗性研究設計法(Quasi-Experimental Design),採取組內對照前後測方法,係針對乳癌住院患者進行中醫的治療,以中藥介入以及透過問卷的訪查,透過蒐集並觀察二十七名未曾接受過乳癌中醫治療的新收案患者,以臨床上經常使用的FACT-G 生活品質量表,進行中醫介入前後生活品質的評估。
結果:本研究發現透過中醫介入在FACT-G 生活品質量表上的分數都有所改善,且在功能、生理、情緒項目達到統計上的顯著差異(P<0.05)。
結論:由結果得知,中醫確實能對乳癌患者在住院化療期間生活品質上有所助益,也希望未來能對乳癌患者在整體療程上帶來更大幫助。
【關鍵詞】乳癌、生活品質、中醫、用藥模式、FACT-G
Wei-Jen Chen1,2 Chi-Hui Liao3 Li-Cheng Zheng1,4
Hsin-Hua Li1 Bo-Chyuan Chen1*
1Department of Chinese Medicine, Dalin Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation,
Chia-Yi, Taiwan
2Department of Environmental and Occupational Health, College of Medicine, National Chen
Kung University, Tainan, Taiwan
3Department of Chinese Medicine, Chi Mei Medical Center, Tainan, Taiwan
4Institute of Gerontology, National Chen Kung University, Tainan, Taiwan
【Summary】
Breast cancer is the most common cancer among women in the world. In every 47 minutes, there was one woman who were newly diagnosed of breast cancer in Taiwan, with an average age of about 54 year-old. The incidence of breast cancer in women in our country is not as high as that in western women, but perhaps due to the effects of westernized diet, late marriage and late pregnancy,the incidence of breast cancer is not only younger but also increasing year by year.
With the recent cancer registration report statistics and the Chinese top ten cause of death report, the incidence of breast cancer and the death rate all reach the first step. The conventional treatment of breast cancer were chemotherapy, radiotherapy and surgery. However, whether in the symptoms of breast cancer, or side effects caused by surgery, chemotherapy and radiotherapy, patient’s discomfort symptoms impacted their life quality. This study aimed at treating patients with breast cancer hospitalized by traditional Chinese medicine (TCM). With TCM intervention and questionnaire survey, we collected and observed 27 newly recruited patients who have not received any TCM treatment of breast cancer. The FACT- G quality of life table were used to patients before and after the intervention of Chinese medicine intervention. From the results of the study, we found that the quality of Life Scale were improved after interventional treatment of Chinese medicine patients, and with statistically significant differences in functional, physiological and emotional items (P<0.05), the results show that Chinese medicine can really help patients with breast cancer in the quality of life. We also revealed the medicine pattern in these patients and compared with the NHIRD study in 2013.
 Keywords Breast cancer, Life quality, Chinese medicine, Medicine pattern,
FACT-G